A 50-year-old male, recently arrived from a region known for endemic infectious diseases, presents to an outpatient clinic for a follow-up visit. He was initially seen for an unrelated complaint, but during the physical examination, a raised, erythematous plaque measuring approximately 6 cm in diameter was noted on his left elbow, which he reported as being present for several months. Upon further inquiry, he mentions a long-standing decrease in sensation over this area. Physical examination reveals complete anesthesia to light touch and pinprick over the lesion and extending distally. There is also a palpable thickening of the ulnar nerve proximally to the lesion. A biopsy performed during his last visit confirmed granulomatous inflammation with evidence of acid-fast bacilli. His recent laboratory work-up is detailed below. Given the clinical presentation and biopsy findings, what is the most appropriate multi-drug therapy regimen, and what long-term neurological complication should be actively monitored?